Figure 3.

Forskolin enhancement of miniature EPSC (mEPSC) frequency is greater in secondary cells from morphine-tolerant rats. A,B,C, Representative current traces with miniature synaptic events (A) and plots of cumulative distribution of mEPSC frequency (B) and amplitude (C) before and during application of forskolin (10 μM) in the same saline control cell. D,E,F, Current traces (D) and plots of mEPSC distribution data (E,F) from a tolerant cell.