Table 3

Number of validated mRNA targets of miRNAs that were differentially up- or down-regulated by SNL nerve injury
miRNA identifier RPM mean HA + LA (sham) diff-reg abs. value, by subtraction     No. of verified mRNA targets       Target genes relevant to pain physiology
Differentially regulated miRNA
rno-miR-378b 49.4 0.457    0
rno-miR-322-3p 30.1 0.494    2      -
rno-miR-30d-5p 10,117 0.132     5       Bdnf
rno-miR-493-3p 73.1 0.316    0
rno-miR-1839-5p 110.9 0,278  0
rno-miR-125b-5p 3147.6 0.265     45       Tnf, Stat3
rno-miR-369-3p 12.8 0.189    0
rno-let-7f-2-3p 9.9 0.567    0
rno-miR-340-3p 10.2 0.561    1      -
rno-miR-6331 12.8 0.467    0
rno-miR-379-5p 194.7 0.278      0
Canonical miRNA of unique sequence isomiR (diff-reg of isomiR)
rno-miR-101a-3p 1735.9 0.079    28      -
rno-miR-130a-3p 470.8 0.160    16       Tac1
Differential expression at baseline (HA_sham vs. LA_sham) all pools
rno-miR-184 25.2 0.550    4      -
rno-miR-6325 16.4    0.114      0

Bali et al.

Bali et al. Molecular Pain 2014 10:22   doi:10.1186/1744-8069-10-22

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