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A clinical genetic method to identify mechanisms by which pain causes depression and anxiety

Mitchell B Max1*, Tianxia Wu2, Steven J Atlas3, Robert R Edwards4, Jennifer A Haythornthwaite4, Antonella F Bollettino1,6, Heather S Hipp1,6, Colin D McKnight1,6, Inge A Osman1,6, Erin N Crawford1,6, Maryland Pao5, Jemiel Nejim1,6,7, Albert Kingman2, Daniel C Aisen1,6, Michele A Scully1,6, Robert B Keller8, David Goldman6 and Inna Belfer1,6

1 Clinical Pain Research Section, Division of Intramural Research, National Institute of Dental and Craniofacial Research, National Institutes of Health, DHHS, Bethesda, MD, USA

2 Statistics Core, Division of Population and Health Promotion Sciences, National Institute of Dental and Craniofacial Research National Institutes of Health, DHHS, Bethesda, MD, USA

3 General Medicine Division and the Clinical Epidemiology Unit, Medical Services, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

4 Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA

5 Office of the Clinical Director, National Institute of Mental Health, National Institutes of Health, DHHS, Bethesda, MD, USA

6 Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, DHHS, Rockville, MD, USA

7 Howard Hughes Medical Institute, Bethesda, MD, USA

8 Maine Spine and Rehabilitation, Portland, ME, USA

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Molecular Pain 2006, 2:14 doi:10.1186/1744-8069-2-14

Published: 19 April 2006

Additional files

Additional File 1:

Galanin receptor-2 gene polymorphisms and 1 year SF-36-MH

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