Figure 1.

Reduced second phase of formalin-induced nociceptive behavior in DN MEK mice. Time course of nociceptive behavior following 2 % formalin injection in the hind paws of either male (A) or female (B) wild type or DN MEK littermate mice. n = 12–14 (male mice) per group, and 8–10 (female mice) per group. For this and the following graphs, data are presented as mean ± S.E.M. **p < 0.01, ***p < 0.001.