|
Association of six GABRB1 markers with movement scores in sciatica patients |
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| dbSNP ID |
Allele1 |
Allele2 |
Genotype |
Count |
Movement Score |
p Value* |
|
|
||||||
| rs4694846 |
A |
G |
1/1 |
125 |
11.35 |
0.1862 |
| 1/2 |
136 |
10.85 |
||||
| 2/2 |
49 |
10.81 |
||||
|
|
||||||
| rs17461905 |
A |
G |
1/1 |
222 |
10.83 |
0.1219 |
| 1/2 |
84 |
11.46 |
||||
| 2/2 |
4 |
11.73 |
||||
|
|
||||||
| rs13107066 |
A |
C |
1/1 |
103 |
11.17 |
0.8874 |
| 1/2 |
136 |
10.84 |
||||
| 2/2 |
71 |
11.09 |
||||
|
|
||||||
| rs6813436 |
A |
G |
1/1 |
4 |
10.53 |
0.6383 |
| 1/2 |
68 |
11.29 |
||||
| 2/2 |
238 |
10.96 |
||||
|
|
||||||
| rs7439087 |
A |
G |
1/1 |
148 |
10.73 |
0.2294 |
| 1/2 |
131 |
11.29 |
||||
| 2/2 |
31 |
11.19 |
||||
|
|
||||||
| rs 6290 |
T |
C |
1/2 |
42 |
10.93 |
0.8447 |
| 2/2 |
268 |
11.04 |
||||
|
|
||||||
| Haplotype analysis |
No. of haplotype 211212 (GAAGAC) |
|||||
| 2 |
8 |
8.5 |
0.0025 |
|||
| 1 |
52 |
10.3 |
||||
| 0 |
248 |
11.3 |
||||
|
p values shown are for additive model, which assumes that each copy of the uncommon allele alters the movement score by a similar amount, and uncorrected for examining 121 SNPs in 22 haplotype blocks in 14 genes. | ||||||
Mishra et al. Molecular Pain 2007 3:20 doi:10.1186/1744-8069-3-20 |
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