Figure 1.

The average time course of the response of C-fibers during the 60 sec period after injection of simplified inflammatory soup was not significantly different in TRPV4^+/+ and TRPV4^-/- mice (unpaired t-test, p > 0.05). The bin width is 1 sec. A. The open bars represent activity evoked by simplified inflammatory soup in TRPV4^+/+ C-fibers (n = 11), and B. The filled bars represent action potentials evoked in TRPV4^-/- C-fibers (n = 13).