Rearing behavior. General activity of the three strains of mice (C57BL/6J, TRPV1 k.o., hairless SKH1-Hrhr) was assessed by monitoring rearing activity. The amount of time (sec) per rearing event was calculated and plotted over several test sessions, completed over the course of 2.5 weeks. There was a significant increase in the time/event ratio for the hairless and C57BL/6J strains over time; however, there were no between strain differences at the later time points, indicating a similar level of accommodation for the strains. *denotes values significantly higher than the first session (P < 0.05).
Neubert et al. Molecular Pain 2008 4:43 doi:10.1186/1744-8069-4-43