Table 1

Rearing behavior.

STRAIN (Mean ± SEM)

A. EVENTS

Session

Hairless

C57BL/6J

TRPV1 k.o.


1

103.3 ± 9.6

50.6 ± 5.3

53.1 ± 3.8

2

77.8 ± 12.8

50.6 ± 5.5

71.6 ± 10.4

3

*58.7 ± 6.4

34.1 ± 5.1

54.8 ± 14.1

4

70.1 ± 8.0

44.6 ± 7.8

48.3 ± 6.8

5

72.5 ± 10.5

31.8 ± 3.2

40.1 ± 9.7

6

*58.0 ± 8.2

33.0 ± 4.7

52.4 ± 8.3

7

*51.0 ± 5.8

28.9 ± 5.2

37.5 ± 6.3

Significance level

(F6,176 = 3.5, P = 0.003)

(F6,69 = 2.9, P = 0.014)

(F6,60 = 1.5, P = 0.201)


B. DURATION

Session

Hairless

C57BL/6J

TRPV1 k.o.


1

57.4 ± 6.1

38.6 ± 5.0

48.5 ± 5.7

2

59.5 ± 8.5

38.5 ± 3.1

56.0 ± 7.2

3

45.5 ± 7.0

31.3 ± 4.2

41.7 ± 7.1

4

52.1 ± 7.3

41.6 ± 5.3

54.6 ± 9.1

5

52.1 ± 7.3

34.6 ± 3.2

36.3 ± 8.3

6

46.9 ± 7.5

30.2 ± 2.8

39.4 ± 7.1

7

51.2 ± 7.5

26.0 ± 4.0

37.2 ± 7.9

Significance level

(F6,168 = 0.46, P = 0.837)

(F6,69 = 1.9, P = 0.093)

(F6,60 = 1.2, P = 0.324)


General activity of the three strains of mice (C57BL/6J, TRPV1 k.o., hairless SKH1-HRHR) was assessed by determining the number of rearing events and duration of the rearing events over the 7-sessions. There was a significant decrease in rearing events for the hairless and C57BL/6J strains (ANOVA, *P < 0.05).

Neubert et al. Molecular Pain 2008 4:43   doi:10.1186/1744-8069-4-43

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