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Increased chemokine signaling in a model of HIV1-associated peripheral neuropathy

Sonia K Bhangoo1,2 email, Matthew S Ripsch3 email, David J Buchanan4 email, Richard J Miller1 email and Fletcher A White3,5 email

Molecular Pharmacology, Northwestern University, Chicago IL USA

National Institute of Dental and Cranial Research, National Institutes of Health, Bethesda, MD, USA

Cell Biology, Neurobiology & Anatomy, Loyola University, Chicago, Maywood, IL USA

Neuroscience Graduate Program, Loyola University, Chicago, Maywood, IL USA

Anesthesiology, Loyola University, Chicago, Maywood, IL USA

author email corresponding author email

Molecular Pain 2009, 5:48doi:10.1186/1744-8069-5-48

Published: 12 August 2009

Additional files

Additional file 1:

CXCR4 and CCR2 chemokine receptor immunoreactivity in naïve animals. CCR2 receptor protein (A) and mRNA (C) expression levels are absent from lumbar DRG taken from naïve rats. Unlike the CCR2 receptor, the CXCR4 chemokine receptor is constitutively expressed in naïve DRG. CXCR4 protein (B) and mRNA (D) expression levels are present in mainly non-neuronal cells in naive lumbar DRG.

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