Figure 3.

Reversal of L-NAMA-induced inhibition of LTP of fEPSP by cADPR, an endogenous agonist of the RyR. Perfusion with 50 μM L-NAME for 1 h before HFS of LT inhibited the induction of LTP (P < 0.001), which was reversed by co-application of L-NAME and 5 μM cADPR for 1 h before HFS (P < 0.001) (control, n = 5; L-NAME, n = 6; L-NAME + cADPR, n = 5).

Cheng et al. Molecular Pain 2010 6:1   doi:10.1186/1744-8069-6-1
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