Pharmacological dissociation between mechanical allodynia and dynamic weight bearing (gait) changes following SNI injury in CD-1 mice. Symbols in A-C represent mean ± S.E.M. von Frey withdrawal thresholds (g; solid symbols) and CatWalk ipsilateral hind paw print intensity (0-250; open symbols) prior to SNI (baseline; BL) and on post-operative day 14, both prior to (Pre) and subsequent to (time post-injection in min is listed) administration of 10 mg/kg morphine (A), 75 mg/kg gabapentin (B), or topical EMLA (C). *p < 0.05 compared to same-test BL.
Mogil et al. Molecular Pain 2010 6:34 doi:10.1186/1744-8069-6-34