Experimental design paradigm. Acupuncture needle manipulation was performed at an acupoint ST36 (Zusanli, arrow pointing to red dot) or a nonmeridian-point focus approximately 2-3 cm distant laterally (NMP, arrow pointing to green dot) on the right leg, respectively. Functional run incorporated the NRER paradigm, incorporating 1.5 min needle manipulation, preceded by 1 min rest epoch and followed by 12.5 min rest scanning.
Bai et al. Molecular Pain 2010 6:73 doi:10.1186/1744-8069-6-73