GSE represses CFA stimulated P-p38 expression in TNC neurons and glial cells. Sections of spinal cord were obtained from untreated animals (CON), animals treated with GSE (GSE), animals injected with CFA (CFA), or animals pretreated with GSE prior to an injection with CFA (GSE + CFA). (A) Images of sections of the TNC stained for P-p38 are shown in the top panels. The bottom panels represent the same sections co-stained P-p38 and DAPI. (B) The average fold change ± SEM of P-p38 staining intensity from control values is reported (n = 3 independent experiments) * P < 0.01 when compared to control levels while # P < 0.01 when compared to CFA stimulation. Magnification bar = 50 μm.
Cady et al. Molecular Pain 2010 6:91 doi:10.1186/1744-8069-6-91