Tamoxifen induces recombination in the DRG of adult AvCreERT2 mouse. Animals were injected (ip) for 5 consecutive days (2 mg per day). A - X-gal staining of adult DRG neurons from induced and un-induced mice. Neutral red was used for counterstaining. B - Quantification of recombination events in DRG of untreated and tamoxifen-treated animals. Data are presented as mean ± SEM. Statistical analysis - unpaired T-test, p ≤ 0.01. Scale bars = 40 μm.
Lau et al. Molecular Pain 2011 7:100 doi:10.1186/1744-8069-7-100