X-gal staining in whole-mount tissues from adult mice. Cre mediated recombination was detected in adult Advillin-Cre mice crossed with R26R mice for lacZ expression. Organs were collected and stained with X-gal. Representative pictures are shown. A. brain from Cre expressing mice and B. Cre negative animals. C. close up of midbrain region of A. D. brainstem. E. and F. trigeminal ganglia from Advillin-Cre mice and littermate controls, respectively. G. vestibular ganglion. H. DRG. I. unstained spinal cord with a stained DRG. J. circumvallate taste buds in the tongue. K. foliate taste buds in the tongue. L. tongue from control mice. X-gal negative M. skin N. superior cervical ganglia, and O. liver from Cre expressing mice. CRE: Advillin-Cre mice. CTR: wildtype littermates controls. Scale bar: 1 mm.
Zurborg et al. Molecular Pain 2011 7:66 doi:10.1186/1744-8069-7-66