The effects of intra-VL PAG microinjections of vehicle (0.05% DMSO in ACSF), ONO-DI-004 (0.1 pg) (A, C) or L355677 (10 pg) (B, D) on the ON cell tail flick-evoked burst of firing (A and B) and OFF cell tail flick-evoked pause (C and D) in sham and SNI rats 7 days after surgery. Each histogram represents the mean ± S.E.M of 6-7 neurons of different treated groups of rats. * indicates significant differences vs sham/vehicle and° versus SNI/vehicle. P values < 0.05 were considered statistically significant.
Palazzo et al. Molecular Pain 2011 7:82 doi:10.1186/1744-8069-7-82